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Metyrapone is used for the medical control of hypercortisolism in Cushing's syndrome (ACTH dependent or independent). The aim for medical treatment is to achieve pre-operative control of hypercortisolism, or for control of residual disease persisting post-operatively (TSS, adrenalectomy). It is not for long term definitive treatment/cure, only as an adjunct (surgery is the aim for cure in most causes of Cushing's syndrome). Metyrapone hence acts by inhibiting adrenal steroidogenesis. One side effect is hirsutism (in women) because of the excess androgen precursors created. The other commonly used agent for medical treatment of Cushing's is ketoconazole (an anti-fungal agent). This does not exhibit the side effect of hirsutism.

Fluticasone propionate is a synthetic (man-made) corticosteroid that is used on the skin (topically). The naturally-occurring corticosteroid is cortisol or hydrocortisone produced by the adrenal gland. Corticosteroids have potent anti-inflammatory actions and also suppress the immune response. Similar drugs include betamethasone dipropionate (Diprolene), clobetasol propionate (Temovate), halobetasol propionate (Ultravate), betamethasone dipropionate (Diprosone), desoximetasone (Topicort), halcinonide (Halog), amcinonide (Cyclocort), triamcinolone acetonide (Kenalog), fluocinolone acetonide (Synalar), hydrocortisone butyrate (Locoid), hydrocortisone valerate (Westcort), and mometasone furoate (Elocon). The FDA approved topical fluticasone propionate in December, 1990.

  • Bronchiectasis (Acquired, Congenital) Bronchiectasis has three types:
    • 1) cylindrical bronchiectasis,
    • 2) saccular or varicose bronchiectasis,
    • 3) and cystic bronchiectasis.
    Causes of bronchiectasis include:
    • infection,
    • environmental exposure, drug or alcohol abuse,
    • and alpha-1 antitrypsin (congenital).
    Symptoms of bronchiectasis include:
    • shortness of breathe,
    • fatigue,
    • chronic cough,
    • bloody sputum,
    • and wheezing.
    Treatment for bronchiectasis include antibiotics and possibly surgery.
  • Drug Interactions Drug interactions occur frequently. Get facts about the types of drug interactions, what substances or other things that may interact with drugs such as OTC drug and prescription drugs, vitamins, food(s) (grapefruit), and laboratory tests. Find out how to protect yourself from potential drug interactions.
  • Drugs: What You Should Know About Your Drugs Important information about your drugs should be reviewed prior to taking any prescription drug. Side effects, drug interactions, warnings and precauctions, dosage, what the drug is used for, what to do if you miss a dose, how the drug is to be stored, and generic vs. brand names.
  • Eosinophilic Esophagitis Eosinophilic esophagitis is an inflammation of the esophagus. Eosinophilic esophagitis has many causes including acid reflux, heartburn, viruses, medications that become stuck in the esophagus, allergy, asthma, hay fever, allergic rhinitis, and atopic dermatitis. Eosinophilic esophagitis symptoms include difficulty swallowing food, abdominal pain, chest pain, and heartburn.
  • fluticasone and salmeterol oral inhaler Advair Diskus, Advair HFA (fluticasone propionate and salmeterol oral inhaler) is an inhalant drug used to treat
    • asthma,
    • chronic bronchitis, and
    • chronic obstructive pulmonary disease (COPD).
    Side effects include:

    Cleocin Suspension  
    RX: Cleocin suspension 2tsp tid x14D Cleocin suspension is available as: 150mg/5ml - 6 ounce bottles. How many bottles do you need to dispense to … Pharmacy Flow rate question  
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    You have a 15g vial of medication with instructions to add to have a concentration of 375mg/mL. What is the powder volume in the vial? … Insulin Calculation  
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    Is test propionate good

    is test propionate good

    Cleocin Suspension  
    RX: Cleocin suspension 2tsp tid x14D Cleocin suspension is available as: 150mg/5ml - 6 ounce bottles. How many bottles do you need to dispense to … Pharmacy Flow rate question  
    You have a solution of Drug H/100,000-U/L, and an infusion apparatus labeled 60gtt/ml. The flow rate required to deliver a dose of 20U/min would be: … Pharmacy Compounding math  
    How many 100 mg Drug T capsules would be needed to compound the following prescription? Rx: % Drug T, 10% glycerin, qs 500ml with Isopropyl alcohol. … Pharmacy Business Math  
    In your pharmacy, performance metrics are constantly measured to evaluate the effectiveness of order prescription order processing. What is the percentage … Formula (Pharmacy) Math  
    You have a 15g vial of medication with instructions to add to have a concentration of 375mg/mL. What is the powder volume in the vial? … Insulin Calculation  
    How many mL of U100 insulin will you need to add to a 1L bag of so it contains 40 units of insulin? A. B. C. D. … Click here to ask a question you have.

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