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Important Safety Information for VECTICAL ® (calcitriol) Ointment

Indication: VECTICAL ® Ointment is indicated for the topical treatment of mild to moderate plaque psoriasis in adults 18 years and older. Adverse Events: In controlled clinical studies, the most commonly reported adverse reactions (≥ 3%) were lab test abnormality, urine abnormality, psoriasis, hypercalciuria, pruritus, and skin discomfort. Warnings/Precautions: The maximum weekly dose should not exceed 200 g. Avoid contact with eyes, lips and face. VECTICAL ® Ointment should be used with caution in patients receiving medications known to increase the serum calcium level, such as thiazide diuretics and in patients receiving calcium supplements or high doses of Vitamin D. If aberrations in parameters of calcium metabolism are noted discontinue VECTICAL ® Ointment until these normalize. Avoid excessive exposure of VECTICAL ® Ointment treated areas to either natural or artificial sunlight.

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Visit /medwatch or call 1-800-FDA-1088 (1-800-332-1088).

Click here for Full Prescribing Information for VECTICAL ® Ointment

The efficacy of CLOBEX® (clobetasol propionate) Lotion, % in psoriasis and atopic dermatitis has been demonstrated in two adequate and well-controlled clinical trials. The first study was conducted in patients with moderate to severe plaque psoriasis. Patients were treated twice daily for 4 weeks with either CLOBEX® (clobetasol propionate) Lotion, % or vehicle lotion. Study results demonstrated that the efficacy of CLOBEX® Lotion, % in treating moderate to severe plaque psoriasis was superior to that of vehicle.

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