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It was in late 2005 that the status of methasterone, in addition to that of four other designer steroids, as an AAS was brought to public awareness by an article published in the Washington Post . [12] Don Catlin of the UCLA Olympic Laboratory, who conducted the studies, noted methasterone’s similarity to drostanolone. A warning by the FDA was issued soon after to the general public as well as to the distributor, Designer Supplements LLC, for the marketing of this compound. [13] Methasterone was subsequently added to the World Anti-Doping Agency (WADA) list of prohibited substances in sport. [14] Despite all of this, methasterone has resurfaced within the supplement industry on several occasions since its banning by WADA. [15]

Some bodybuilders and athletes use trenbolone esters for their muscle-building and otherwise performance-enhancing effects. [5] Such use is illegal in the United States and many other countries. The DEA classifies trenbolone and its esters as Schedule III controlled substances under the Controlled Substances Act . [18] Trenbolone is classified as a Schedule 4 drug in Canada [19] and a class C drug with no penalty for personal use or possession in the United Kingdom . [20] Use or possession of steroids without a prescription is a crime in Australia . [21] The infamous "duchess" cocktail administered to Russian athletes at the Sochi Winter Olympics consisted of oxandrolone , a metenolone ester, and a trenbolone ester. [22]

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